.contenedor {
    width: 100%;
    height: 400px;
    border: 2px dashed #ccc;
    position: relative;
  }

  .draggable, .dragable-dos {
    width: 100px;
    height: 100px;
    background-color: green;
    color: #fff;
    text-align: center;
    line-height: 100px;
    position: absolute;
    cursor: grab;        
  }

  .dragable-dos {
    background-color: red;
  }

  .draggable:active, .draggable-dos:active {
    cursor: grabbing;
  }   

        
<div class="contenedor">
  <div class="draggable">
    <p>Arrástrame</p>
  </div>
  <div class="draggable-dos">
    <p>Elemento 2</p>
  </div>
</div>  

        
let draggie = new Draggabilly('.draggable');

        
const contenedor = document.querySelector('.contenedor');
const draggable = document.querySelector('.draggable');
const draggableDos = document.querySelector('.draggable-dos');

const draggie = new Draggabilly(draggable, {
  containment: contenedor,
  axis: 'x', 
});

const draggie_dos = new Draggabilly(draggableDos, {
  containment: true,   
  
});

draggie_dos.setPosition( 260, 25 );

        
const contenedor = document.querySelector('.contenedor');
const draggable = document.querySelector('.draggable');
const draggableDos = document.querySelector('.draggable-dos');
const toggleButton = document.getElementById('toggleDraggable');

const draggie = new Draggabilly(draggable, {
  containment: contenedor,
  grid: [ 50, 50 ],
  disabled: true, 
});

const draggie_dos = new Draggabilly(draggableDos, {
  containment: true,
  handle: '.handle',

});

draggie_dos.setPosition(260, 25);

let isDraggableEnabled = false; 

toggleButton.addEventListener('click', () => {
  isDraggableEnabled = !isDraggableEnabled; 

  if (isDraggableEnabled) {
    draggie.enable(); 
    toggleButton.textContent = 'Arrastrar Habilitado'; 
  } else {
    draggie.disable(); 
    toggleButton.textContent = 'Arrastrar Inhabilitado'; 
  }
});

        
<div class="contenedor">
    <div class="draggable">Arrástrame</div>
    <div class="draggable-dos">
      <div class="handle">Asa</div>    
    </div>
  </div>
<button id="toggleDraggable">Arrastrar Habilitado</button>